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NRTIs block an HIV enzyme called reverse transcriptase. By blocking reverse transcriptase, NRTIs prevent HIV from multiplying and can reduce the amount of HIV in the body.
Written by Natee, Translated by Saroh, Medically Approved by Dr. Wichakorn, on 30 JUNE 2022
Trade Name:
TAFICITA®
Generic Name:
Tenofovir alafenamide 25 mg + Emtricitabine 200 mg
Mechanism of Action:
NRTIs block an HIV enzyme called reverse transcriptase. By blocking reverse transcriptase, NRTIs prevent HIV from multiplying and can reduce the amount of HIV in the body.
Indication:
It is used to treat HIV infection.
Other Indication:
• Descovy is also FDA-approved for use in certain at-risk individuals as an agent for HIV pre-exposure prophylaxis (PrEP).
• As a stand-alone agent, tenofovir alafenamide (brand name: Vemlidy) is FDA-approved for chronic HBV infection treatment.
Side effect:
Many side effects from HIV medicines, such as nausea or occasional dizziness, are manageable. See the AIDSinfo fact sheet on HIV Medicines and Side Effects for more information. If any of the side effects get serious tell your doctor.
Drug Interaction:
You should not take Descovy with medicines containing:
• tenofovir alafenamide
• tenofovir disoproxil
• lamivudine
• adefovir dipivoxil
Other types of medicine:
• rifabutin, rifampicin, and rifapentine
• emtricitabine and tipranavir
• anticonvulsants, used to treat epilepsy
• herbal remedies used to treat depression and anxiety containing (Hypericum perforatum)
• Tell your doctor if you are taking these or any other medicines. Do not stop your treatment without contacting your doctor.
Pregnancy:
• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
• Do not breast-feed during treatment with Descovy.
Alcohol, Drug and Supplement:
A total of 200 drugs are known to interact with TAFICITA (emtricitabine / tenofovir alafenamide) categorized as 125 major, 72 moderate, and 3 minor interactions. For more information, please Click
Availability:
Prescription only. Contact PULSE CLINIC.
References:
https://www.drugs.com/descovy.html
https://www.drugs.com/pro/descovy.html
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