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Comprehensive Metabolic Panel (CMP-14) with eGRF Blood Test

• Glucose - Blood sugar level, the most direct test to screen for diabetes and also used in diabetes management.
• Kidney Profile
• Bun or Urea Nitrogen (BUN) - An indicator of kidney function.  
• Creatinine, Serum - An indicator of kidney function.  
• Bun/Creatinine Ratio - Calculated by dividing BUN by creatinine. This ratio can suggest conditions including dehydration or intestinal bleeding.
• Estimated Glomerular Filtration Rate (eGFR) - Measures kidney function to determine kidney disease stage and detect early kidney damage.

• Liver Panel
• Protein, Total - Assists in determining liver and kidney function and nutritional health.
• Albumin Serum - One of the major proteins essential for the healthy function of the liver and kidney. 
• Globulin, Total - One of the major proteins that assist the blood to clot properly and also comprises infection-fighting antibodies. 
• Albumin/Globulin Ratio - Calculated by dividing albumin by globulin. When paired with other test results, this ratio can assist in the diagnosis of a variety of liver problems. 
• Bilirubin, Total - Aids in the detection of hepatitis, sickle cell, anemia, cirrhosis, alcohol, and drug abuse. High concentrations may result in jaundice.
• Alkaline Phosphatase - A protein vital in detecting bone disorders and liver disease.
• Aspartate Aminotransferase (AST or SGOT) - An enzyme helpful in evaluating liver function. An elevated level is an indication of hepatitis. 
• Alanine Aminotransferase (ALT or SGPT) - An enzyme helpful in identifying liver damage. Abnormalities may represent liver disease.

• Fluids & Electrolytes
• Sodium - One of the major salts in body fluid. Sodium is important in water balance and the electrical activity of nerves and muscles.
• Potassium - Helps to control the nerves and muscles.
• Chloride - Similar to sodium, it helps to maintain the body's electrolyte balance.
• Carbon Dioxide, Total - Used to help detect, evaluate, and monitor electrolyte imbalances.
• Calcium - A mineral essential for the development and maintenance of healthy bones and teeth. It is also important for the normal function of muscles, nerves, and blood clotting.

Lipid Panel includes: Cholesterol, total; high-density lipoprotein (HDL) cholesterol; low-density lipoprotein (LDL) cholesterol (calculation); triglycerides; very low-density lipoprotein (VLDL) cholesterol (calculation)

Testosterone, Total and Free 
Testosterone is a hormone that causes male characteristics. Blood level is used by men to investigate abnormal sexual development and sexual dysfunction. Small amounts are produced in women's ovaries and these levels are tested to evaluate virilization. The concentration of free testosterone is very low, typically <2% of total testosterone concentration. In most men and women, >50% of total circulating testosterone is bound to sex hormone-binding globulin, SHBG, and most of the other is bound to albumin.1 Routinely available assay methods used to measure total testosterone aren't sensitive enough to accurately quantitate the free testosterone fraction directly. Free testosterone is estimated in this test by a direct, analogue radioimmunoassay method. This test uses a labeled testosterone analogue that has a low binding affinity for both SHBG and albumin but is bound by antitestosterone antibody used in the assay. Since the analogue is unbound in the plasma, it competes with free testosterone for binding sites on an antitestosterone antibody that is immobilized on the surface of the polypropylene tube.

SHBG stands for sex hormone binding globulin. It's a protein made by the liver and attaches itself to sex hormones found in both men and women. These hormones are: Testosterone, the main sex hormone in men. Dihydrotestosterone (DHT), another male sex hormone.

Homocysteine helps diagnose B12/folate deficiencies and to identify patients who may be at risk for heart disease and/or strokes.

C-Reactive Protein, High Sensitivity (CRP,hs) Measurement of CRP by high sensitivity CRP assays may add to the predictive value of other markers used to assess the risk of cardiovascular and peripheral vascular disease.  Increases in CRP values are nonspecific. CRP is an indicator for a wide range of disease processes and should not be interpreted without a complete clinical history. Recent medical events resulting in tissue injury, infections, or inflammation, which may cause elevated CRPlevels, should also be considered when interpreting results. Serial analysis of CRP should not be used to monitor the effects of treatment.

Thyroid Panel with Thyroid-Stimulating Hormone (TSH) - Thyroid function is crtical to your metabolism and affects your energy level, heart rate, weight control, and more. The thyroid-stimulating hormone is produced in the pituitary gland and stimulates the production of thyroid hormones. The TSH helps identify an underactive or overactive thyroid state. This comprehensive evaluation of your thyroid hormone levels includes: T-3 Uptake, T4, Free Thyroxine Index (T7),  and Thyroid-Stimulating Hormone (TSH).

Free T3: Test for evaluating thyroid function and assessing abnormal binding protein disorders.

Free T4: Free T4 may be indicated when binding globulin (TBG) problems are perceived, or when conventional test results appear to be inconsistent with clinical observations. It is normal in those with high thyroxine-binding globulin hormone binding who are euthyroid (i.e., free thyroxin should be normal in nonthyroidal diseases). It should also be normal in familial dysalbuminemic hyperthyroxinemia.

Estradiol -  Estrogen is a group of hormones that is primarily responsible for the development of female sex organs and secondary sex characteristics. There are three main estrogen fractions that are estrone (E1), estradiol (E2), and estriol (E3). Estradiol (E2) is produced in women mainly in the ovary. In men, the testes and adrenal glands are the principal source of estradiol. In women, normal levels of estradiol provide for proper ovulation, conception, and pregnancy, in addition to promoting healthy bone structure and regulating cholesterol levels.

DHEA,S - Dehydroepiandrosterone sulfate (DHEAS) is an androgen, a male sex hormone that is present in the blood of both men and women. It has a role to play in developing male secondary sexual characteristics at puberty, and it can be metabolized by the body into more potent androgens, such as testosterone and androstenedione, or can be changed into the female hormone estrogen. DHEAS is produced by the adrenal cortex, the outer layer of the adrenal glands, with smaller amounts being produced by the woman's ovaries and man's testes. DHEAS secretion is controlled by the pituitary hormone adrenocorticotropic hormone (ACTH) and by other pituitary factors. Since DHEAS is primarily produced by the adrenal glands, it is useful as a marker for adrenal function. Adrenal tumors, cancers, and hyperplasia can lead to the overproduction of DHEAS. While elevated levels may not be noticed in adult men, they can lead to amenorrhea and visible symptoms of virilization.

IGF-1 Somatomedin-C (SC) Produced in the liver in response to stimulation by growth hormone secreted by the pituitary gland. This insulin-like growth factor level is used to evaluate disturbances of growth and to monitor treatment with growth hormones.

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Frequently Asked Questions

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