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Post-Exposure Prophylaxis PEP
Written by Icetim, Translated by Saroh, Medically Approved by Dr. Wichakorn, on 30 JUNE 2020
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Trade Name:
Dolutegravir Tablets®
Generic Name:
Dolutegravir 50 mg
Mechanism of Action:
Integrase Inhibitors
Indication:
Treat HIV1 infection together with other antiretroviral medicines.
Other Indication:
Post-Exposure Prophylaxis (PEP)
Side effect:
Common side effect
• Nausea or vomiting
• Trouble sleeping, tiredness, and headache.
• Fever
Uncommon side effect
• Liver problems
• Muscle or joint aches
• Allergy (Rash,redness or swelling of the eyes swelling of the mouth, face, lips, or tongue problems breathing)
Drug Interaction:
• Antacids or laxatives that contain calcium, magnesium, or aluminum (such as Amphojel, Di-Gel Maalox, Milk of Magnesia, Mylanta, Pepcid Complete, Rolaids, Rulox, Tums, and others), or the ulcer medicine sucralfate (Carafate)
• Buffered medicine
• Vitamin or mineral supplements that contain calcium or iron (but if you take Tivicay with food, you can take these supplements at the same time)
Pregnancy:
• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine
• Possible increased risk of neural tube defects
Alcohol, Drug and Supplement:
Recommend to take dolutegravir at least two hours before or six hours after supplements.(Products that contain aluminum, calcium, iron, magnesium and/or other minerals)
Availability:
Prescription only. Contact PULSE CLINIC.
References:
https://us.tivicay.com
https://www.drugs.com/pregnancy/dolutegravir.html